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FIGURE 8. Molecular finding in BAs. A, Results of molecular studies and BRAF IHC on 21 BAs. B, Hemotoxylin and eosin of a BRAF V600E mutant BA (patient 8, case 2). C, BRAF V600E staining shows cytoplasmic positivity in both luminal and apical cells.

Journal: American Journal of Surgical Pathology

Article Title: Bronchiolar Adenoma

doi: 10.1097/pas.0000000000001086

Figure Lengend Snippet: FIGURE 8. Molecular finding in BAs. A, Results of molecular studies and BRAF IHC on 21 BAs. B, Hemotoxylin and eosin of a BRAF V600E mutant BA (patient 8, case 2). C, BRAF V600E staining shows cytoplasmic positivity in both luminal and apical cells.

Article Snippet: IHC antibodies included p40 (clone BC28, 1:200; Biocare), Thyroid transcription factor-1 (TTF1) (clone 8G7G3/1, prediluted; Ventana), CK5/6 (clone D5/16B4, prediluted; Ventana), Napsin A (clone IP64, 1:200; Leica), BRAF V600E (clone VE1, 1:800; Spring Bio), ALK (clone D5F3, prediluted; Cell Signaling), and CC10 (goat polyclonal IgG, 1:50; Santa Cruz).

Techniques: Mutagenesis, Staining